麻疹病毒IgG ELISA檢測(cè)試劑盒

英文名稱：Measles virus IgG enzyme-linked immunosorbent assay kit

廣州健侖生物科技有限公司

（廣州健侖生物科技有限公司是集研制開發(fā)、銷售、服務(wù)于一體的優(yōu)良企業(yè),公司產(chǎn)品涉及臨床快速診斷試劑、食品安全檢測(cè)試劑，違禁品快速檢測(cè)，動(dòng)物疾病防疫檢測(cè)試劑，免疫診斷試劑、臨床血液學(xué)和體液學(xué)檢驗(yàn)試劑、微生物檢驗(yàn)試劑、分子生物學(xué)檢驗(yàn)試劑、臨床生化試劑、有機(jī)試劑等眾多領(lǐng)域，同時(shí)核心代理Panbio、FOCUS、Qiagen、IBL、CORTEZ、Fuller、Inbios、BinaxNOW、LumuQuick、日本富士、日本生研等多家有名診斷產(chǎn)品集團(tuán)公司產(chǎn)品，致力于為商檢單位、疾病預(yù)防控制中心、海關(guān)出入境檢疫局、衛(wèi)生防疫單位,緝毒系統(tǒng)，戒毒中心，檢驗(yàn)檢疫單位、生化企業(yè)、科研院所、醫(yī)療機(jī)構(gòu)等機(jī)構(gòu)與行業(yè)提供*、高品質(zhì)的產(chǎn)品服務(wù)。此外，本公司還開展食品、衛(wèi)生、環(huán)境、藥品等多方面的第三方檢測(cè)服務(wù)。）

主要用途：用于定量測(cè)定人血清、腦脊液或血漿中的麻疹抗體。

產(chǎn)品規(guī)格：96T/盒

存儲(chǔ)條件：4-8℃

保質(zhì)期：18個(gè)月

我司同時(shí)還提供、美國(guó)FOCUS、西班牙DIA、美國(guó)trinity等試劑盒：

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【產(chǎn)品介紹】

（1）潛伏期約10日（6～18天）。曾經(jīng)接觸過(guò)麻疹患兒或在潛伏期接受被動(dòng)免疫者，可延至3-4周。在潛伏期內(nèi)可有輕度體溫上升。

（2）前驅(qū)期也稱發(fā)疹前期，一般為3～4天。表現(xiàn)類似上呼吸道感染癥狀：①發(fā)熱見(jiàn)于所有病例，多為中度以上發(fā)熱；②咳嗽、流涕、流淚、咽部充血等，以眼癥狀突出，結(jié)膜發(fā)炎、眼瞼水腫、眼淚增多、畏光、下眼瞼邊緣有一條明顯充血橫線（Stimson線），對(duì)診斷麻疹極有幫助。③麻疹黏膜斑，在發(fā)疹前24～48小時(shí)出現(xiàn)，為直徑約1.0mm灰白色小點(diǎn)，外有紅色暈圈，開始僅見(jiàn)于對(duì)著下臼齒的頰黏膜上，但在一天內(nèi)很快增多，可累及整個(gè)頰黏膜并蔓延至唇部黏膜，黏膜疹在皮疹出現(xiàn)后即逐漸消失可留有暗紅色小點(diǎn)；④偶見(jiàn)皮膚蕁麻疹，隱約斑疹或猩紅熱樣皮疹，在出現(xiàn)典型皮疹時(shí)消失；⑤部分病例可有一些非特異癥狀，如全身不適、食欲減退、精神不振等。但體溫稍有下降。嬰兒可有消化系統(tǒng)癥狀，嘔吐、腹瀉等。

（3）出疹期多在發(fā)熱后3-4天出現(xiàn)皮疹。體溫可突然升高至40～40.5℃，皮疹為稀疏不規(guī)則的紅色斑丘疹，疹間皮膚正常，出疹順序也有特點(diǎn)：始見(jiàn)于耳后、頸部、沿著發(fā)際邊緣，24小時(shí)內(nèi)向下發(fā)展，遍及面部、軀干及上肢，第3天皮疹累及下肢及足部。病情嚴(yán)重者皮疹常融合，皮膚水腫，面部水腫變形。大部分皮疹壓之褪色，但亦有出現(xiàn)淤點(diǎn)者。全身有淋巴結(jié)腫大和脾腫大，并持續(xù)幾周，腸系膜淋巴結(jié)腫大可引起腹痛、腹瀉和嘔吐。闌尾黏膜的麻疹病理改變可引起闌尾炎癥狀。疾病極期特別是高熱時(shí)常有譫妄、激惹及嗜睡狀態(tài)，多為一過(guò)性，熱退后消失，與以后中樞神經(jīng)系統(tǒng)合并癥無(wú)關(guān)。此期肺部有濕性羅音，X線檢查可見(jiàn)肺紋理增多。

(1) incubation period of about 10 days (6 to 18 days). Those who have been exposed to measles or passive immunization in the incubation period may be extended to 3-4 weeks. In the incubation period may have mild body temperature rise.

(2) Precursor Period also known as pre-eruption, usually 3 to 4 days. Symptoms similar to the upper respiratory tract infection: fever found in all cases, mostly moderate to moderate fever; cough, runny nose, tears, throat congestion, prominent in ocular symptoms, conjunctival inflammation, eyelid edema, increased tear, photophobia, The lower eyelid margin has an obvious congestion line (Stimson line), extremely helpful in the diagnosis of measles. Measles mucosa spots, 24 to 48 hours before the onset of rash appeared as a diameter of about 1.0mm gray dots, a red halo outside, beginning only seen in the buccal mucosa facing the lower molars, but soon increased in one day, Can affect the entire buccal mucosa and spread to the lip mucosa, mucosal rash disappears after the rash may appear dark red dots can be left; ④ occasional skin urticaria, vague rash or scarlet fever-like rash disappears in the presence of a typical rash ; ⑤ some cases may have some non-specific symptoms, such as general malaise, loss of appetite, lack of energy and so on. But the temperature dropped slightly. Infants may have digestive symptoms, vomiting, diarrhea and more.

(3) rash more than 3-4 days after the onset of fever rash. Body temperature can suddenly rise to 40 ~ 40.5 ℃, the rash is sparse irregular red rash, rash skin is normal, the order of the rash also has characteristics: first seen in the ear, neck, along the hairline edge, down within 24 hours Development, throughout the face, trunk and upper extremities, the third day of the rash involving the lower extremities and feet. Patients with severe rash often confluence, skin edema, facial edema deformation. Most of the skin rash pressure fade, but there are also those who have spots. Systemic lymph nodes and splenomegaly, and for several weeks, mesenteric lymph nodes can cause abdominal pain, diarrhea and vomiting. Appendectomy pathological changes in measles can cause appendicitis symptoms. Extreme disease especially during high fever, often delirium, irritability and lethargy state, mostly transient, disappear after the heat back and forth, has nothing to do with the subsequent central nervous system complications. This period of lung wet rales, X-ray examination showed increased lung texture.

【檢測(cè)原理】

ELISA（酶聯(lián)免疫吸附測(cè)定）是涉及的免疫學(xué)過(guò)程在抗體檢測(cè)的感染領(lǐng)域尤其得到證實(shí)。該基于抗體和抗原的特異性相互作用的檢測(cè)反應(yīng)。至為此目的，使用賽潤(rùn)ELISA classic的微量滴定板的測(cè)試條傳染性病原體特異性抗原在患者樣品中的結(jié)合包被的抗體存在。 其他用堿性磷酸酶標(biāo)記二抗檢測(cè)由此形成的免疫復(fù)合物。 該酶催化a反應(yīng)過(guò)程中，無(wú)色底物對(duì)硝基苯磷酸酯在有色產(chǎn)物中對(duì)硝基苯酚轉(zhuǎn)化。 反應(yīng)產(chǎn)物的信號(hào)強(qiáng)度正比于樣品中的抗體濃度用光度法檢測(cè)。

麻疹病毒IgG ELISA檢測(cè)試劑盒

【試劑盒的組成】

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【公司名稱】 廣州健侖生物科技有限公司
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不受管制而迅速增殖的細(xì)胞通常會(huì)轉(zhuǎn)變成良性腫瘤或惡性腫瘤。良性腫瘤不會(huì)擴(kuò)散到身體其他部份，或是侵入別的組織，除非腫瘤的生長(zhǎng)壓迫到重要的器官，否則也不會(huì)影響生命。惡性腫瘤則會(huì)侵略其他器官，轉(zhuǎn)移到身體其他部位而危害生命。
引起基因突變的物質(zhì)被稱為致癌物質(zhì)，又以其造成基因損傷的方式可分為化學(xué)性致癌物與物理性致癌物。例如接觸放射性物質(zhì)，或是一些環(huán)境因子，例如，香煙、輻射、酒精。還有一些病毒可將本身的基因插入細(xì)胞的基因里中，激活癌基因。但突變也會(huì)自然產(chǎn)生，所以即使避免接觸上述的致癌因子，仍然無(wú)法*預(yù)防癌癥的產(chǎn)生。發(fā)生在生殖細(xì)胞的突變有可能傳至下一代。
現(xiàn)知有1000多種化學(xué)物質(zhì)具致癌作用，如黃曲霉素可致肝癌，香煙的燃燒物可致肺癌，亞硝胺可致食道癌。物理致癌因素中，放射線可致白血病，過(guò)強(qiáng)紫外照射和局部慢性刺激可致皮膚癌。病毒、寄生蟲感染等生物因素可能與鼻咽癌、肝癌有一定關(guān)系。家族遺傳、免疫水平、精神刺激、營(yíng)養(yǎng)狀態(tài)以及內(nèi)分泌活動(dòng)等因素亦對(duì)腫瘤的發(fā)生起重要作用。尤其是精神因素與癌癥的近來(lái)倍受重視。
生活方式的影響
生活方式對(duì)于癌癥發(fā)生確實(shí)是有影響，例如香煙、飲食、運(yùn)動(dòng)、酒精、曬太陽(yáng)以及性病等。
zui近幾十年的研究中，zui為確定的發(fā)現(xiàn)就是抽煙和癌癥間密切的相關(guān)性，許多流行病學(xué)研究也已經(jīng)證實(shí)這樣的關(guān)系。根據(jù)美國(guó)的數(shù)據(jù)顯示，隨著吸煙人數(shù)增加，肺癌的死亡率急劇升高。
同時(shí)有越來(lái)越多的研究顯示，癌癥發(fā)生也和體內(nèi)褪黑激素的量相關(guān)，當(dāng)需要長(zhǎng)時(shí)間待在明亮的環(huán)境下，例如晚班的工人。或是睡眠時(shí)間較短的人，褪黑激素表現(xiàn)量也會(huì)偏低，而癌癥的發(fā)病率較高。
癌癥的傳染
有些并非發(fā)生在人類的癌癥可能能經(jīng)由傳染而引起，例如發(fā)生于狗的史狄可氏肉瘤（Sticker's sarcoma）。有病患接受細(xì)菌，由于移植器官中帶有腫瘤，結(jié)果得到癌癥。這是目前已知較類似經(jīng)由傳染而得的例子。
癌癥的遺傳

Unregulated and rapidly proliferating cells often turn into benign or malignant tumors. Benign tumors do not spread to other parts of the body, or invade other tissues, and do not affect life unless the growth of the tumor compresses into vital organs. Malignant tumors will invade other organs, transfer to other parts of the body and endanger life.
Substance causing mutations are called carcinogens, but also its way to cause genetic damage can be divided into chemical carcinogens and physical carcinogens. Such as exposure to radioactive material, or some environmental factors, such as cigarettes, radiation, and alcohol. Still others can insert their own genes into the cell's genes and activate oncogenes. But mutations also occur naturally, so even if you avoid contact with these oncogenic factors, you still can not compley prevent cancer. Mutations that occur in germ cells are likely to reach the next generation.
Now known to have more than 1,000 kinds of chemical substances with carcinogenic effects, such as aflatoxin can cause liver cancer, the combustion of cigarettes can cause lung cancer, nitrosamines can cause esophageal cancer. Among the physical carcinogenic factors, radiation can cause leukemia, too strong UV irradiation and local chronic irritation can cause skin cancer. Viruses, parasitic infections and other biological factors may be related to nasopharyngeal carcinoma, liver cancer have a certain relationship. Family genetic, immune levels, mental stimulation, nutritional status and endocrine activities and other factors also play an important role in tumorigenesis. In particular, the link between mental factors and cancer has drawn much attention recently.
The impact of lifestyle
Lifestyles do have an impact on cancer, such as cigarettes, diet, exercise, alcohol, sunbathing, and sexually transmitted diseases.
The most definitive finding in recent decades of research is the close correlation between smoking and cancer, and many epidemiological studies have confirmed this relationship. According to the U.S. data, as the number of smokers increases, the mortality rate of lung cancer has risen sharply.
In the meantime, more and more studies show that the incidence of cancer is also related to the amount of melatonin in the body when it takes a long time to stay in a bright environment, such as night shift workers. Or people who sleep for a short time, melatonin performance will be low, while the incidence of cancer is higher.
Infection with cancer
Some cancers that are not in humans can be caused by infection, such as Sticker's sarcoma in dogs. Patients receive the bacteria, and as a result of the tumor in the transplanted organ, the result is cancer. This is an example known to be more contagious now.
Genetics of cancer